A summary on the workshop on pharmacokinetic modelling

Although the COVID-19 pandemic prevented us from organizing the on-site workshop, we managed to successfully transfer the event to the internet. Thanks to that, we were able to invite more world-known speakers and reach out to the broader audience of veterinary pharmacologists from all over the world. More than 80 participants representing 6 continents have registered and 62 of them actively participated in the event. 

The NAWA Workshop lasted two days and gave the opportunity to listen to lectures given by esteemed specialists in advanced methods of pharmacometric modelling and simulation. Among them were both Polish scientists - prof. Paweł Wiczling (Gdańsk Medical University), as well as scholars from the Netherlands - prof. Ronette Gehring (Utrecht University), USA - dr Benjamin Schneider (Agios Pharmaceuticals) and dr Joseph Smith (University of Tennessee), and from France - dr Monika Twarogowska (Lixoft, Simulations Plus).

The NAWA Workshop consisted of not only informative lectures, but also some practical instructions and hands-on training with a powerful modelling software Monolix Suite. A dedicated license code has been sent to all participants so they could practice working with Monolix on their own computers while the Monolix team was explaining the workflow online. Additionally, veterinary case studies have been presented so underline the application aspects of modelling and simulation in veterinary pharmacology.

Below you can find links to the workshop videos and the agenda. The video may not work on mobile devices.

Download workshop agenda


Introduction



Paweł Wiczling (Gdańsk Medical University, Poland)
The role of pharmacokinetic-pharmacodynamic models in research – part 1



Paweł Wiczling (Gdańsk Medical University, Poland)
The role of pharmacokinetic-pharmacodynamic models in research – part 2



Joseph Smith (University of Tennessee, USA)
Introduction to Non-linear Mixed Effects Modelling



Ronette Gehring (Utrecht University, the Netherlands)
Compartmental modeling – from classical to PBPK – part 1



Ronette Gehring (Utrecht University, the Netherlands)
Compartmental modeling – from classical to PBPK – part 2



Monika Twarogowska (Lixoft, Simulations Plus, France, USA)
Introduction to Monolix Suite and hands-on session



Benjamin Schneider (Agios Pharmaceuticals, USA)
Veterinary case study with Monolix Suite – using a simulation tool for
benazepril dose optimization in the congestive heart failure in dogs